En la esclerosis sistémica, el esófago se afecta en un 90%, seguido de los tramos anorrectal (%), gástrico ( 70%), colon (%) e intestino delgado. La esclerodermia es un relativamente infrecuente enfermedad reumática autoinmunitaria que afecta la piel y otros órganos del cuerpo. La esclerosis sistémica es una enfermedad autoinmune del tejido conectivo, que se caracteriza por un depósito excesivo de tejido colágeno y otros.

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Surgical management of the hand in scleroderma. BMJ,pp. J Am Acad of Dermatol, 54pp. Other abnormalities described in this disease include peripheral large vessels stiffness and secondary cardiac involvement due escleerosis pulmonary and systemic arterial hypertension.

Losartan therapy for Raynaud’s phenomenon and scleroderma. Sistemuca iloprost treatment of Raynaud’s phenomenon secondary to systemic sclerosis. Case report A 50 year old male, with no relevant family history, who was diagnosed of subclinical hypothyroidism and early scleroderma has been follow-up by Rheumatology and Dermatology. Geographic variation in the prevalence of Raynaud phenomenon.

Semin Arthritis Rheum, 35pp.

Úlceras digitales en la esclerosis sistémica | Seminarios de la Fundación Española de Reumatología

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Placebo controlled study showing therapeutic benefit of iloprost in the treatment of Raynaud’s phenomenon. Scleroderma patients nailfold videocapillarooscopic patterns esclersois with disease subset and disease severity.

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Hemorragia por telangiectasias en paciente con esclerosis sistémica

Are you a health professional able to prescribe or dispense drugs? Intravenous N-Acetylcysteine for treatment of Raynaud’s secondary to systemic sclerosis: Lancet, 2pp.

The pathogenesis of digital ulcers differs depending on their location and occurs in up to half of all patients with limited or diffuse systemic sclerosis at some point during their disease. Resolution of severe digital ulceration during a course of bosentan therapy. The knowledge of the pathogenesis of systemic sclerosis to molecular level will lead to new treatment strategies. Mechanism of sustained monomorphic ventricular tachycardia in systemic sclerosis.


Increased whole blood platelet aggregation in patients with Raynaud’s phenomenon with or without systemic sclerosis. Clin Rheumatol, 20pp. Circulation,pp.

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Br J Clin Esflerosis, 31pp. Arthritis Rheum, 42pp. Pathogenesis of systemic sclerosis scleroderma. The relationship of arrhytmias and conduction disturbances to other manifestations of cardiopulmonary disease in progressive systemic sclerosis PSS.

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Treatment of Raynaud’s phenomenon with the selective serotonin reup-take inhibitor fluoxetine. Bosentan eistemica for cutaneous fibrosis in systemic sclerosis.

Ann Intern Med, 97pp. Angina pectoris, myocardial infarction, and sudden cardiac death with normal coronary arteries: In contrast, the results of treatment of fibrosis are discouraging and the D-penicilamine continues being a matter of controversy.

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